The biggest breakthrough since IVF

New Hope Fertility Center is proud to lead the medical community to the latest breakthrough in reproductive medicine: Nuclear Transfer (3-Person IVF). While information on this amazing technology is currently limited, please use this FAQ and feel free to contact us for more information and scheduling appointments.

Is 3-Parent IVF for you?

We encourage couples considering this new technique to contact our offices and inquire about availability and further details.  New Hope performed the first single case study of Nuclear Transfer, however all future cases will be performed by DARWIN LIFE.
Please email for eligibility and to apply.


What is 3-parent IVF?

3-Parent IVF, or 3-Person IVF, is the technique of using genetic material from 3 people to create a healthy embryo. The term 3-Parent IVF is misleading because the child still only has 2 parents. Our treatment is called H.E.R. IVF and is similar to 3 parent IVF.

nuclear transfer ivf 3 parent ivf

What is H.E.R. IVF?

H.E.R. IVF stands for Human Egg Rejuvenation In Vitro Fertillization. The “R” also stands for “reconstitution” and “reconstruction. The technical term for H.E.R. IVF is NUCLEAR TRANSFER.

What is Nuclear Transfer? How does it work?

Nuclear Transfer is the process of transferring the nucleus of an unhealthy egg or an egg of poor quality into a healthy or high quality donor egg, before fertilization.

The nucleus is the center of a cell and contains all the DNA required to form human life. Outside the nucleus is a liquid called Cytoplasm. Cytoplasm contains organelles called Mitochondria, which are the power houses of the cell. They are responsible for, among other things, how the body functions (breathing, hearing, heart function, etc.) on a cellular level. There is special kind of DNA, mtDNA, or Mitochondrial DNA, which is passed maternally through conception. This DNA is located on what we call Mitochondrial Spindles. During Nuclear Transfer, unhealthy mtDNA is left behind in the patient egg’s cytoplasm.

Where can I read more information about nuclear transfer?

For more information on H.E.R. IVF (3-parent IVF) please visit

Also, Dr. John Zhang and his team has blogged about this and you can read the blogs on:

Does Nuclear Transfer work?

We are excited for the results of this ground-breaking procedure to be revealed at this year’s ASRM conference in Utah on OCT 19th.

What diseases can nuclear transfer help with?

The primary function of H.E.R. IVF or Nuclear Transfer is to prevent the inheritance of diseased mitochondria. Mitochondrial Disease, also known as Mito-disease, is the primary disorder currently addressed. Other applications will be discussed in the future.

Can H.E.R. IVF or Nuclear Transfer help me?

At New Hope Fertility Center, each person receives individualized care with a custom treatment plan based on their specific medical background. Determining whether or not Nuclear Transfer is suitable for you will be determined on a case by case basis upon evaluation.

How long does nuclear transfer process/cycle take?

While the number of cycles needed is different patient to patient, the treatment overall takes slightly longer than traditional IVF.

When will more information become available?

The world’s first live birth baby boy was born from Spindle Nuclear transfer in April, 2016. His birth was announced at the ASRM conference in Salt Lake City, UTAH and in New York City at the Assisted Reproductive Technology World Congress. Dr. Zhang’s presentation covered technical and ethical questions and more info is available at

LEARN MORE ABOUT 3-Person In Vitro Fertilization

(Click the links below for more infertility information)