Zaher Merhi, MD, FACOG, HCLD

Director Of Research And Development In IVF Technologies

Board Certified, Reproductive Endocrinology and Infertility Specialist (REI)

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Dr. Merhi is an internationally recognized fertility doctor, lecturer, editor, and grant reviewer. He has 3 American Board certifications: Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, and High-Complexity Clinical Laboratory Director (HCLD). His training and faculty appointments included Albert Einstein College of Medicine, NYU School of Medicine, and University of Vermont. He is currently a Professor and the Fellowship Program Director at SUNY Downstate University.

Dr Merhi is an active researcher and honoree of many grant awards. His research focuses on “obesity/overweight and reproduction,”  improving egg quality, Polycystic Ovary Syndrome (PCOS), thin endometrial lining, Minimal Stimulation IVF (Mini IVF), and Natural IVF for women with diminished ovarian reserves (DOR), especially those with very low Anti-Mullerian Hormone (AMH). Most recently his research focuses on Ovarian Rejuvenation, Ozone Sauna, and Needle-Free IVF. Dr. Merhi is also experienced in treating women who have had Bariatric Surgery (surgery for weight loss), is a strong proponent of the LGBTQ community, and has proudly served the Jewish Community for over a decade.

He has published over 80 manuscripts in high-quality medical journals and many book chapters. He continues to present his research at national and international scientific conferences. Various media outlets have reported on his research including N.Y. Times, CNN, MSNBC, ABC News, NY Post, Medscape, Fox News, Hollywood Life, Women’s Health, Daily Mail, and Allure.

He serves as a Chair, Moderator, Reviewer, and Member on several committees such as American Society for Reproductive Medicine (ASRM), New England Fertility Society, Society for Reproductive Investigation (SRI), and Endocrine Society. He has also served as a grant reviewer for the National Institute of Health (NIH). He evaluates, edits, and reviews manuscripts for over 70 scientific journals. He uses his extensive research background to provide the most up-to-date medical advances in infertility treatments to his patients.

Dr. Merhi Speaks English, French, Arabic, and Spanish.

Message from Dr. Merhi

“I look to form a personal relationship with patients to establish confidence and provide superior fertility and endocrinology care.”

Awards & Special Recognition

Publications

Awards & Special Recognition

2019
Society for Reproductive Investigation (SRI)/Bayer Discovery and Innovation Grant
2017
American Society of Reproductive Medicine (ASRM) Research Grant
2014
Internal Grant Program Award, University of Vermont College of medicine, Burlington VT
2014
Ferring Pharmaceuticals Grant Award Recipient, Investigator Initiated Trial
2013
ASRM Grant Recipient
2013
Teaching Award (twice) for Medical Students, University of Vermont College of medicine, Burlington VT
2012
Young Research Investigator Award, Albert Einstein College of Medicine and Yeshiva University, Bronx NY
2012
Henry L. Moses Prize recipient, Basic Science category, Albert Einstein/Montefiore Medical Center, Bronx, NY
2010
Ferring Pharmaceuticals Grant Award Recipient, New England Fertility Society, Tewksbury, MA
2007
T32 recipient for The Aging Institute at Albert Einstein College of Medicine and Yeshiva University, Bronx NY
2007
Grant recipient from Resnick Gerontology Center, Albert Einstein College of Medicine and Yeshiva University, Bronx NY
2007
Clinical Investigator Workshop recipient, Endocrine Society, San Francisco, CA
2007
The Ralph Wynn Award; Teaching Resident Award. Department of OB/GYN, Maimonides Medical Center, Brooklyn NY
2007
Grant recipient from Maimonides Research and Development Foundation, Brooklyn NY
2007
The Brooklyn Gynecological Society of Brooklyn and Staten Island. Participant Award, Residents’ Night, April 18
2007
New York Obstetrical Society Resident and Fellow Research Night Award for outstanding resident paper, April 10
2006
Grant recipient from Maimonides Research and Development Foundation, Brooklyn NY
2005
Teaching Resident Award. Department of OBGYN, Maimonides Medical Center, Brooklyn NY

Publications

Zhang JJ, Yang M, Merhi Z. Reproductive potential of mature oocytes after conventional ovarian hyperstimulation for in vitro fertilization. Int J Gynaecol Obstet. 2016 Jan 15

Merhi Z, Thornton K, Bonney E, Cipolla MJ, Charron MJ, Buyuk E. Ovarian kisspeptin expression is related to age and to monocyte chemoattractant protein-1. J Assist Reprod Genet. 2016 Feb 15

Hessol NA, Holman S, Minkoff H, Cohen MH, Golub ET, Kassaye S, Karim R, Sosanya O, Shaheen C, Merhi Z. Menstrual cycle phase and single tablet antiretroviral medication adherence in women with HIV. AIDS Care. 2016;28:11-21

Zhang JJ, Merhi Z, Yang M, Bodri D, Chavez-Badiola A, Repping S, van Wely M. Minimal stimulation IVF vs conventional IVF: a randomized controlled trial. Am J Obstet Gynecol. 2016;214:96.e1-8

Sciaranghella G, Wang C, Hu H, Anastos K, Merhi Z, Nowicki M, Stanczyk FZ, Greenblatt RM, Cohen M, Golub ET, Watts DH, Alter G, Young MA, Tsibris AM. CCR5 Expression Levels in HIV-Uninfected Women Receiving Hormonal Contraception. J Infect Dis. 2015;212:1397-401

Zhang JJ, Feret M, Chang L, Yang M, Merhi Z. Obesity adversely impacts the number and maturity of oocytes in conventional IVF not in minimal stimulation IVF. Gynecol Endocrinol. 2015;31:409-13.

Merhi Z, Polotsky AJ, Bradford AP, Buyuk E, Chosich J, Phang T, Jindal S, Santoro N. Adiposity Alters Genes Important in Inflammation and Cell Cycle Division in Human Cumulus Granulosa Cell. Reprod Sci. 2015;22:1220-8

Merhi Z, Doswell A, Marilyn Cipolla M. Vitamin D Alters Genes Involved in Follicular Development and Steroidogenesis in Human Cumulus Granulosa Cells. J Clin Endocrinol Metab. 2014;99:1137-45.

Merhi Z, Irani M, Doswell AD, Ambroggio J. Follicular Fluid Soluble Receptor for Advanced Glycation End-Products (sRAGE): A Potential Indicator of Ovarian Reserve. J Clin Endocrinol Metab. 2014;99:E226-33

Merhi Z. Advanced Glycation End-Products: Pathway of Potentially Significant Pathophysiological and Therapeutic Relevance for Metabolic Syndrome in Menopausal Women. J Clin Endocrinol Metab. 2014;99:1146-8.

Irani, Minkoff H, Seifer DB, Merhi Z. Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women with PCOS. J Clin Endocrinol Metab. 2014;99:886-90

12. Merhi Z. Advanced Glycation End-Products and their Relevance in Female Reproduction. Hum Reprod. 2014;29:135-45.

Berger DS, Zapantis A, Merhi Z, Younger J, Polotsky AJ, Jindal SK. Embryo quality but not pronuclear score is associated with clinical pregnancy following IVF. J Assist Reprod Genet. 2014;31:279-83

Merhi Z, Buyuk E, Berger D, Zapantis A, Israel D, Chua Jr S, Jindal S. Leptin Suppresses Anti-Mullerian Hormone Gene Expression through JAK2/STAT3 Pathway in Luteinized Granulosa Cells of Women Undergoing In Vitro Fertilization. Hum Reprod. 2013;28:1661-9

Merhi Z, Zapantis A, Berger DS, Jindal SK. Determining an anti-mullerian hormone cutoff level to predict clinical pregnancy following in vitro fertilization in women with severely diminished ovarian reserve. J Assist Reprod Genet. 2013;30:1361-5.

Berger DS, Merhi Z, Hogge WA, Ferrell RE. Mannose binding lectin genotypes are not associated with increased risk of unexplained recurrent pregnancy loss. J Assist Reprod Genet. 2013;30:723-7

Merhi Z, Keltz J, Zapantis A, Younger J, Berger D, Lieman H, Jindal S, Polotsky A. Male Adiposity Impairs Clinical Pregnancy Rate by In Vitro Fertilization without Affecting Day 3 Embryo Quality. Obesity. 2013;21:1608-12

Merhi Z, Pollack SE. Pituitary origin of persistently elevated human chorionic gonadotropin in a patient with gonadal failure. Fertil Steril. 2013;99:293-6

Merhi Z, Seifer D.B.,Weedon J, Adeyemi O., Holman S., Anastos K., Golub E., Young M., Karim R., Greenblatt R., Minkoff H. Circulating Vitamin D Correlates with Serum Anti-Mullerian Hormone Levels in Late Reproductive-Aged Women: Women’s Interagency HIV Study. Fertil Steril. 2012;98:228-34.

Aslam M, Merhi Z, Ahmed S, Kuzbari O, Seifer D, Minkoff H. Changes in plasma müllerian-inhibiting substance and brain-derived neurotrophic factor after chemotherapy in premenopausal women. Fertil Steril. 2011;95:1790-3.

Aslam M., Vemareddy K., Merhi Z., Minkoff H. Unusual case of postpartum hepatitis due to hereditary haemochromatosis. BJOG. 2010;117:620-2.

Todd B*, Merhi Z*, Shu J, Etgen A, Neal-Perry G. Hypothalamic insulin-like growth factor-I receptors are necessary for hormone-dependent luteinizing hormone surges: implications for female reproductive aging. Endocrinology. 2010;151:1356-66. *both are first authors

Lederman M, Lebesgue D, Gonzalez V, Shu J, Merhi Z, Etgen A, Neal-Perry G. Age-related LH surge dysfunction correlates with reduced responsiveness of hypothalamic anteroventral periventricular nucleus kisspeptin neurons to estradiol positive feedback in middle-aged rats. Neuropharmacology. 2010;58:314-20.

Mahmoud M., Merhi Z. Computed tomography-assisted laparoscopic removal of intraabdominally migrated levonorgestrel-releasing intrauterine systems. Arch Gynecol Obstet. 2010;281:627-30.

Haberman S, Feldman J, Merhi Z, Markenson G, Cohen W, Minkoff H. Effect of clinical-decision support on documentation compliance in an electronic medical record. Obstet Gynecol. 2009;114:311-7.

Mahmoud M., Fridman D., Merhi Z. Subserosal Misplacement of Essure Device Manifested by Late Onset Acute Pelvic Pain. Fertil Steril. 2009;92:2038.e1-3.

Merhi Z., Minkoff H, Messerlian G, Macura, Feldman J and Seifer D. Plasma Brain-Derived Neurotropic Factor in Women after Bariatric Surgery. Fertil Steril. 2009;91:1544-8.

Merhi Z., Durkin H, Feldman J, Macura J, Rodriguez C and Minkoff H. The Effect of Bariatric Surgery on Peripheral Blood Lymphocyte Subsets in Women. Surg Obes Relat Dis. 2009;5:165-71.

Merhi Z., Messerlian G, Minkoff H, Eklund E, Macura J, Feldman J, Rodriguez C, Seifer D. Comparison of Serum and Plasma Measurements of Mullerian Inhibiting Substance. Fertil Steril. 2008;89:1836-7.

Merhi Z., Minkoff H, Macura J, Feldman J, Rodriguez C, Seifer D. Relationship of Bariatric Surgery to Mullerian-Inhibiting Substance Levels. Fertil Steril. 2008;90:221-4.

Arora R., Merhi Z., Khulpateea N., Roth D. and Minkoff H. Ovarian Hyperstimulation Syndrome Following a Molar Pregnancy Evacuation. Fertil Steril. 2008;90:1197.e5-7.

Merhi Z., Haberman S. Syncopal Episode as the Presenting Symptom of Jugular Vein Thrombosis in Pregnancy. J Reprod Med. 2007;52:535-6.

Mahmoud M, Merhi Z. Complete Hydatiform Mole with Surviving Coexistent Twin in a Patient with Sickle Cell Disease. J Reprod Med. 2007;52:567-9.

Merhi Z. And Santoro N. Postmenopausal Virilization after Spousal Use of Topical Androgens. Fertil Steril. 2007;87:976.e13-5.

Awonuga A., Merhi Z., Awonuga M., Samuels T., Waller J., Pring D. Anthropometric Measurements In the Diagnosis of Pelvic Size: An Analysis of Maternal Height and Shoe Size and Computed Tomography Pelvimetric Data. Arch Gynecol Obstet. 2007;276:523-8.

Hammoud A., Merhi Z., Diamond M., Baumann P. Recurrent Pregnancy Loss and Obstetric Outcome. Int J Gynaecol Obstet. 2007;96:28-9.

Awonuga A., Merhi Z., Khulpateea K. An Abdominal Packing Procedure for Intractable Obstetrical and Gynecologic Hemorrhage. Int J Gynaecol Obstet. 2006;93:160-3.

Merhi Z., Awonuga A. Acute Abdominal Pain as the Presenting Symptom of Isolated Iliac Vein Thrombosis in Pregnancy. Obstet Gynecol. 2006;107:468-470.

Rotas M, Haberman S, Merhi Z., Morcos M. Prenatal Diagnosis of Giant Fetal Truncal Hemangioma Using Two and Three- Dimensional Ultrasound With Magnetic Resonance Imaging. J Ultrasound Med. 2006;25:527-31.

Merhi Z., Roberts J, Awonuga A. A Case of 46,X,der(X)t(X;X)(q22.1;p11) Xq22.1?Xqter in a 12 Year Old Girl with Premature Ovarian Failure. Gynecol Obstet Invest. 2006;63:137-139.

Awonuga A, Greenbaum L., Merhi Z., Levgur M., Minkoff H. Vesicovaginal Fistula Associated With Cytomegalovirus Infection In An HIV-infected Patient. Gynecol Obstet Invest. 2006;63:143-145.

Merhi Z., Haberman S, Roberts J, Sobol-Benin G. Prenatal Diagnosis of Palatal Teratoma by 3-Dimensional Sonography and Color Doppler Imaging. J Ultrasound Med. 2005;24:1317-20.

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