Our Mini-IVF™ treatment is our trademarked, unique in vitro fertilization treatment. Like our Natural Cycle IVF, it is a holistic approach to fertility care and seeks to offer a gentle alternative to Conventional IVF. It differs from Natural Cycle IVF in its use of a minimal amount of oral medication to stimulate your ovaries so that they are able to produce the maximum number of "quality" eggs possible in a single cycle. Fertility experts know that the quality eggs (usually 3-5) harvested in a Mini-IVF cycle are the eggs most likely to develop into a healthy baby, even if more were to be produced through hyper-stimulation. When more aggressive IVF drug treatments are used (for example, with the use of many daily injections), although more eggs are produced, those beyond 3-5 are typically not viable and are either discarded prior to implantation or will be prone to failing in a later natural miscarriage.
In general, medication for the Mini-IVF™ treatment includes one Clomid pill consumed once daily, no more than one to three injections of Menopur, and a simple nasal spray of Synarel or an equivalent medicine administered 36 hours prior to egg retrieval. Synarel avoids the need for repeated progesterone injections, which are typically used after the transfer step in conventional IVF. However, because we customize protocols to each individual patient, these vary substantially from case to case.
Like those women who choose Natural Cycle IVF, women who choose the Mini-IVF™ treatment hope to minimize the amount of chemicals and drugs in their lives. Mini-IVF™ treatment can be preferable to natural cycle IVF because it tends to yield more quality eggs each cycle, increasing the chances of pregnancy and providing surplus embryos to freeze for a later cycle.
Additionally, women will choose Mini-IVF™ over conventional IVF to reduce health risks and discomfort caused by ovarian hyper-stimulation (OHSS), to eliminate the pain of daily drug injections (20 to 60 per cycle), to reduce the high cost of drugs in conventional IVF protocols (see New Hope Fertility Center's low IVF fees), to avoid the wait time of two to three months between cycles, and to minimize the potential risk of ovarian and endometrial cancer from prolonged use of high-dose IVF drugs.
The pregnancy success rates for the Mini-IVF™ treatment (averaging 1.1 embryos transferred in each IVF cycle) is competitive with the success rate produced by conventional IVF, where usually two to three embryos are transferred in each IVF cycle; however, these sets of rates are not fully suitable for comparison. Due to the health risks posed by twins or multiple births, New Hope Fertility Center promotes a single-embryo strategy (unless otherwise requested by the patient). Consequently, our Mini-IVF™ treatment pregnancy rates would virtually double, matching and, in some cases, exceeding conventional IVF if we transferred the same number of embryos (two to three or more each cycle) as is standard in conventional IVF. Please refer to the chart below, which compares what you can expect from Conventional and Mini-IVF™ treatments.
New Hope Fertility Center's Mini-IVF™ protocols are gentle, affordable, and successful -- and our clinic is recognized globally as leading experts in this treatment.

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