Metabolomics Clinical Trial

A new groundbreaking non-invasive embryo selection method.

Join our study

You are a healthy woman undergoing an In Vitro Fertilization (IVF) cycle.

We’ve found something you can do to advance reproductive medicine while we help you to become pregnant.

Together we can change the future of many women like you.

There is a widely recognized relationship between embryo metabolism and IVF treatment success. Now it is time to validate this breakthrough in assisted reproduction, as doing so will help many women like you reach their goal of motherhood.

A Ground Breaking
Non-Invasive Embryo Selection Method

Improving embryo selection

Embryo selection for transfer to your womb is the key to improving the success rate of IVF treatments. For now, the only method to help pick the top qualified embryos is chromosomal analysis of a few cells removed from a live embryo. Problems with chromosomes are seen in 30% of young women, and in 80% of women over 40. Working alongside researchers at Overture Life, New Hope Fertility will test a new, non-invasive method of embryo selection called Metabolomics, which is based on the analysis of discarded embryo culture medium. Now, by studying the culture medium used for your embryos, we have a chance to improve embryo selection and IVF success rates.

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Benefits of Metabolomics

  • Save up to $9,000 on your IVF treatment by participating in this study
  • 97.5% consistent with invasive genetic analysis results
  • Automated ranking of best embryos for transfer
  • Highly predictive with ongoing pregnancy
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There are no known risks to you or your embryo associated with collection and analysis of culture medium that would otherwise be discarded. The risk is the same as that of a routine IVF cycle.

Why should
I participate?

Furthering success

You will benefit from this study by having all your viable embryos analyzed by metabolomics at no cost to you! After the first embryo transfer you will receive metabolomics results for all remaining embryos to prioritize your next transfer.

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Your treatment

You will undergo a routine IVF cycle as described in your consent form. Following egg retrieval, your oocytes will be fertilized and cultured for five days. After the fifth day, the culture media the embryo was grown in will be collected and sent to a lab for metabolomic analysis, and then all embryos will be frozen. You will be scheduled for an embryo transfer cycle and will be monitored for up to eight weeks depending on the outcome of your transfer.

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Overture Life is an American biotechnology company which seeks to democratize Assisted Reproductive Technologies (ART) by making them more accessible, simplifying techni- ques, and optimizing resources.

Metabolomics was developed by researchers at Overture life as an alternative to invasive genetic analysis of the embryo. It has been found to be 97.5% consistent with the results of invasive genetic analysis.1

In the words of Dr. Jose A. Horcajadas, inventor of the Meta- bolomics test, “the idea is to not only identify the embryos with chromosomal problems, but to also identify the 30% of genetically normal embryos that do not implant. We are on the way to making reproductive medicine less invasive and more effective, for the benefit of all women. Thank you for your participation, your contribution toward the advance- ment of science is much appreciated”.

1 Sara Cabello-Pinedo et al. A novel non-invasive metabolomics approach to screen embryos for aneuploidy. Fertility&Sterility 2020; Vol 114, Issue 3, Supplement, E5-E6

New Hope Fertility Center – Metabolomics Clinical Trial Contact Questionnaire

This questionnaire is to obtain basic information about you to help us determine your eligibility to enroll in the Metabolomics Clinical Trial study.

Study Reviewed and Approved by
Western Institutional Review Board (WIRB)

Sponsor: Overture Life, Inc.
Principal investigator: Dr. José A. Horcajadas
Study subinvestigator: Dr. John Zhang
Study site: New Hope Fertility Center
Study related phone number: 866-942-4817
Study related email: