What is NICS?
Non-Invasive Chromosomal Screening (NICS) is a type of Preimplantation Genetic Testing for Aneuploidy (PGT-A). It is used to check an embryo’s overall chromosomal status prior to being transferred to the patient’s uterus.
Unlike the traditional embryo screening which requires an embryo biopsy, NICS is a non-invasive procedure that only removes a small sample of culture media surrounding the embryo, and does NOT involve taking cells from the embryo itself, thus causing little to no stress on embryo development.
The development of NICS technology at New Hope Fertility Center marks a huge and truly a momentous achievement, as we are now one of only a handful of centers around the world offering a validated and accurate platform for analyzing embryologic DNA in a completely non-invasive fashion.
Advantages of NICS
- Less embryo manipulation
- Culture media is processed on site (no transportation concerns)
- Avoids disruptive embryo biopsies which have been recently shown to increase the risk of pre-eclampsia and placental problems in pregnancy**
** Fertility and Sterility. “Maternal and neonatal outcomes associated with trophectoderm biopsy”. 2019 Aug;112(2):283-290
Candidates for NICS
- Same indications as routine PGT-A (formerly PGS)
- Any woman desiring prenatal genetic screening to rule out Down Syndrome or other syndromes
- Women desiring to lower the risk of a miscarriage
- Recurrent pregnancy loss (2 or more miscarriages)
- Recurrent implantation failure (multiple failed embryo transfers)